Dear Colleagues:

Platelet-rich plasma (PRP) is a preparation of autologous human plasma with an increased platelet concentration produced by centrifuging a larger volume of a patient’s own blood. PRP is increasingly widely used in tissue repair. PRP is a promising treatment for some musculoskeletal diseases; PRP is involved in the regulation of cell migration, division, differentiation, tissue angiogenesis, extracellular matrix synthesis, and vascular repair of damaged tissues in the process of tissue regeneration and repair. The application in orthopedics, sports medicine, burn plastic surgery, chronic refractory wound repair and many other disciplines has shown satisfactory results.however, evidence of its efficacy has been highly variable depending on the specific indication. Additional high-quality clinical trials with longer follow-up will be critical in shaping our perspective of this treatment option.The purpose of this special issue is to present some of the latest advances in PRP treatment, with the aim of improving the therapeutic effect of PRP patients.